Harvard Heart Letter: December 2007

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Articles in this issue:

Genetic help for a blood-thinner balancing act

The FDA is recommending a genetic test for people prescribed warfarin, to search for variants of certain genes that can affect the drug's effectiveness. But there is not enough evidence yet that the test makes using the drug safer.

A blood pressure problem that's isolated in name only

Isolated systolic hypertension, when the systolic blood pressure is above 140 while the diastolic pressure is below 90, is caused by stiffening of large arteries. Medication may be prescribed, but lifestyle changes will have more impact on overall health.

Heart Beat: Teachable moment

Research has established that heart disease tends to run in families, so if a family member has a heart attack or stroke, it should serve as a motivator for other family members to see their doctors.

Heart Beat: Steering clear of pacemaker infections

A small but growing number of people develop an infection after having a pacemaker or ICD implanted. Research has found that taking antibiotics before the procedure reduces the risk of infection.

Heart Beat: Newer bypass technique may be safer for women

A study found that women who had off-pump bypass surgery had much lower rates of heart attack, stroke, or death during the operation or shortly after, more so than for men.

Heart Beat: ACE, ARB duet questioned

ACE inhibitors and angiotensin-receptor blockers are both used to combat stress hormones, which can contribute to heart failure. Combining them brings additional risks that outweigh any possible benefits.

Heart Beat: Take a shot against heart disease

A study found that heart disease deaths peaked each year during flu season, because the flu can trigger a heart attack or stroke. Those with heart disease, and those at higher risk of getting it, should get a flu vaccine each year.

Heart Beat: Too few get the best therapy for an ailing heart

Cardiac rehabilitation programs have been shown to reduce deaths in the years following a heart attack or stent procedure, but not enough patients participate in the programs.

Ask the doctor: How do I handle conflicting advice about exercise?

Last year, I had an aortic dissection. My surgeon says not to do any cardio or resistance exercise and to keep my heart rate down. My cardiologist says I can do light cardio and resistance exercise but to watch my blood pressure. Whom should I believe?

Ask the doctor: Is yerba mate good for my heart?

Is it true that drinking yerba mate can lower blood pressure and cholesterol?