Many people with acid reflux heartburn end up taking medications for life, but it may not be necessary in all cases. The most effective treatments for acid reflux are drugs in the class called proton-pump inhibitors (PPIs), including omeprazole (Prilosec) and lansoprazole (Prevacid). It is possible to stop taking PPIs, but it must be done gradually. Suddenly stopping often triggers a return of heartburn symptoms. Once off of medications, it is also important to address the underlying causes of heartburn, such as being overweight and eating close to bedtime.
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