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Blood test could find Alzheimer’s disease before symptoms appear

In the journals

Researchers are close to finding early cancer with a blood test. They may soon do the same with Alzheimer's disease. A new blood test called p-tau217 has shown great promise in diagnosing people with the disease, according to findings published online July 28, 2020, by JAMA.

The test looks for a specific type of tau protein in the blood. In people with Alzheimer's, tau protein in the brain forms tangles. Accumulation of tau protein tangles along with beta-amyloid deposits is thought to play a key role in how the disease develops.

Happy holidays?

Here's how to cope when your usual traditions get uprooted.

The holiday season, like just about everything else this year, probably won't look the same as usual. Whether that means going to smaller gatherings without the usual relatives, quarantining when traveling, or staying home entirely, chances are something will be different this year thanks to the COVID-19 pandemic. For many who look forward to a full table at Thanksgiving or a big party on New Year's Eve, these changes are unwelcome, and frankly a little depressing.

In response, people may experience emotions ranging from guilt to loneliness to a feeling of disconnected sadness, says Dr. Hilary Connery, assistant professor of psychiatry at Harvard Medical School.

Should I get a flu shot this year?

Ask the doctors

Q. I'm debating whether I need to get a flu shot this year. Do you think it's worthwhile?

A. The answer to this question is an emphatic yes. It's more important than ever to get a flu shot this year for a number of reasons. First, it will reduce your likelihood of contracting, being hospitalized for, or dying from influenza, which should be reason enough to roll up your sleeve. In addition, if you do get sick with the flu after being vaccinated, the vaccine can reduce the severity of your illness.

Heart-related complications in people hospitalized with the flu

Research we're watching

Serious heart complications are common in people hospitalized with influenza, according to a study published online Aug. 25, 2020, by Annals of Internal Medicine.

Researchers from the CDC looked at the rates of cardiovascular problems in more than 80,000 adults hospitalized with a confirmed case of influenza (commonly called the flu) from 2010 to 2018. Almost 12% had a serious cardiovascular problem, most commonly heart failure or a lack of adequate blood flow to the heart, known as acute coronary syndrome. The body's immune response against the infection can trigger inflammation and other changes that harm the cardiovascular system.

Making special education work for your child during COVID-19

The pandemic has forced parents everywhere to face problems that don’t have clear solutions regarding their children’s schooling. For parents of children with disabilities who receive special education, these concerns are even more challenging, and parental choices are even more difficult.

Beyond trick-or-treating: Safe Halloween fun during the COVID-19 pandemic

Celebrating Halloween by going trick-or-treating or attending a party could be very risky this year. Here are tips to help you and your family stay safe while having fun.

Tips for beating anxiety to get a better night’s sleep

Many people with anxiety disorders have trouble sleeping. That's a problem. Too little sleep affects mood, contributing to irritability and sometimes depression. Vital functions occur during different stages of sleep that leave you feeling rested and energized or help you learn and forge memories. Sleep usually improves when an anxiety disorder is treated. Practicing good "sleep hygiene" helps, too. Here are some steps to take:

  • Go to bed and wake up at the same time every day, even on weekends.
  • Daylight helps set sleep patterns, so try to be outdoors while it's light out for 30 minutes a day.
  • Exercise regularly (but not too close to bedtime). An afternoon workout is ideal.
  • Keep naps short — less than an hour — and forgo napping after 3 p.m.
  • Avoid caffeine (found in coffee, many teas, chocolate, and many soft drinks), which can take up to eight hours to wear off. You may need to avoid caffeine entirely if you have panic attacks; many people who experience panic attacks are extra-sensitive to caffeine.
  • Review your medications with a doctor to see if you are taking any stimulants, which are a common culprit in keeping people up at night. Sometimes it's possible to switch medicines.
  • Avoid alcohol, large meals, foods that induce heartburn, and drinking a lot of fluid for several hours before bedtime.
  • If you smoke, quit. Smoking causes many health problems, including compromising sleep in a variety of ways.
  • Keep your bedroom cool, dark, and quiet, without distractions like TV or a computer. Avoid using an electronic device to read in bed; the light from the screen can trick your brain into thinking it is daytime. If your mattress is uncomfortable, replace it.
  • Reading, listening to music, or relaxing before bed with a hot bath or deep breathing can help you get to sleep.
  • If you don't fall asleep within 20 minutes of turning in (or if you wake up and can't fall back to sleep in 20 minutes), get out of bed and do something relaxing until you feel sleepy.

For additional tips and strategies for living with anxiety, buy Coping with Anxiety and Stress Disorders, a Special Health Report from Harvard Medical School. 

Cultivating joy as a family

The pandemic has been difficult for everyone, but particularly for families. Everyone is feeling so much uncertainty and stress, but one thing we can do is look for ways to create small moments of joy every day. Games, activities, creativity, being outdoors — there are simple, fun ways to be together and make memories.

As family well-being declines, so does children’s behavior

The COVID-19 pandemic is affecting the mental health of people who have not been sick, and parents are being hit particularly hard. A survey of US parents found that these worsening circumstances also affect children’s behavior.

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