Heart Medications Archive

Articles

The lowdown on "good" cholesterol

Long touted as beneficial for heart health, high-density lipoprotein (HDL) is more complicated than experts once thought. Some forms of HDL grab cholesterol from the bloodstream and other tissues and transport it to the liver, where it's recycled or disposed, but other types are neutral or perform the opposite action. Most drugs that raise HDL don't seem to prevent heart disease, and very high HDL levels may even be linked to a higher risk.

Brushing off heart failure symptoms

Heart failure symptoms, such as being tired or out of breath, gaining weight, or having swollen ankles, can be overlooked and attributed to other causes. As a result, heart failure is not usually diagnosed until months or years later, when a person is hospitalized for it. By that point, the risk for dying from heart failure has already risen significantly, sometimes higher than the risk of death from cancer. Someone who has potential heart failure symptoms should talk to a doctor, especially if symptoms are new and if the person has diabetes, heart disease, high blood pressure, obesity, or an unhealthy lifestyle.

What is acute coronary syndrome?

Acute coronary syndrome (ACS) refers to a spectrum of conditions defined by a sudden reduction in blood flow to the heart. Most often, the underlying cause is a gradual buildup of fatty deposits called plaque inside the arteries supplying the heart. ACS includes two distinct types of heart attacks, known as STEMI and NSTEMI, and a serious condition called unstable angina that's often a prelude to a heart attack. All warrant immediate medical attention.

Yoga and high blood pressure

A regular yoga practice may help lower blood pressure. But people with this condition should be cautious about certain poses that place the heart higher than the head (known as inversions).

The changing landscape of LDL lowering drugs

For most people, statins are still the best way to lower harmful LDL cholesterol. But two newer drugs may be promising additions or alternatives for those with stubbornly high LDL levels. Bempedoic acid, which lowers LDL by about 25%, works in a manner similar to statins but may help reduce muscle-related side effects seen with statins. Inclisiran interferes with a protein that’s involved with regulating LDL production in the liver; it lowers LDL by about 50%.

Nitrates in food and medicine: What’s the story?

Nitrates are added to processed meats (such as bacon, ham, and deli meats) and are found naturally in leafy green vegetables (such as spinach and kale). But it’s not clear how crucial these molecules are compared with other components of those foods, as dietary nitrate levels don’t appear to affect heart disease risk. However, nitrate-based drugs are used to treat angina, a common symptom of coronary artery disease.

Living with stable angina

For people with stable angina, which occurs in about two-thirds of people with heart disease, optimal medical therapy is almost always the best treatment. It includes all the medications a person needs to get cholesterol, blood pressure, and blood sugar into a healthy range. Certain medications, including beta blockers, calcium-channel blockers, and nitrates, also help relieve the discomfort of angina.

Have a safe trip!

People with heart-related conditions or risks should take simple precautions when travelling by airplane. These include taking steps to ease stress, such as listening to music or reading a good book; bringing medications in their original containers in carry-on luggage; and not worrying too much about blood clots, which are uncommon during air travel even in people with a history of clots.

Alternatives to warfarin may be safer, more effective for afib

For people with certain types of valvular atrial fibrillation, drugs known as direct oral anticoagulants (DOACs) may be safer and more effective than warfarin (Coumadin). DOACs include apixaban (Eliquis), dabigatran (Pradaxa), and rivaroxaban (Xarelto).

Diastolic blood pressure: Worth a second look?

A diastolic blood pressure reading lower than 60 mm Hg may be linked to an increased risk of heart attack and stroke in people at high cardiovascular risk. Diastolic pressure tends to fall with age. Some people with a low reading have a leaky aortic valve, which interferes with normal blood circulation throughout the heart and causes diastolic pressure to fall. But in people with healthy aortic valves who can be physically active without any symptoms (such as chest pressure, shortness of breath, or lightheadedness), a low diastolic blood pressure should not pose a problem.

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