Special Health Reports

Making Sense of Vitamins and Minerals

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Making Sense of Vitamins and Minerals: How to get the nutrients you need to stay healthy

About half of all Americans routinely take dietary supplements. The most common ones are multivitamin and multimineral supplements. Making Sense of Vitamins and Minerals: How to get the nutrients you need to stay healthy explains the evidence behind the benefits and safety profiles of various vitamins and minerals. It also includes the recommended minimum and maximum amounts you should consume, as well as good food sources of each.

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With so many Americans routinely taking dietary supplements, it's important to have the best science backed information on what you should be putting into your body. In general, studies of people who eat diets rich in fruits, vegetables, nuts, whole grains, and fish show that they consume higher levels of vitamins and minerals from these foods and also have a lower risk of many diseases including heart disease, stroke, diabetes, and cancers.

On the other hand, trials testing the effect of selected vitamins or minerals as pill supplements have mostly shown very little influence on health. The main exception may be fish oil supplements, for which some trials show a lower risk of heart disease, and possibly vitamin D.

This report explains the different types of studies used to assess the benefits and safety profiles of various nutrients. It also includes the recommended minimum and maximum amounts of the vitamins and minerals you should consume, as well as good food sources of each. The special section, “Does your diet deliver the daily recommended dose?” will help you determine whether you’re getting sufficient amounts of vitamins and minerals from your diet, and what to do if you’re not.

Prepared by the editors at Harvard Health Publishing in consultation with Howard D. Sesso, Sc.D., M.P.H., Associate Epidemiologist, Brigham and Women’s Hospital; Associate Professor of Medicine, Division of Preventive Medicine, Harvard Medical School. 46 pages. (2025)

Cast of characters: From vitamin A to zinc

This chapter features a broad overview of the best-known vitamins and minerals. For each nutrient described here, you’ll find the following information:

  • the Recommended Dietary Allowance (RDA) or adequate intake (AI) for people ages 19 and older (with sex and age differences noted when applicable) and a brief description of the nutrient’s role in the body. An RDA is the average daily amount of a nutrient that is sufficient to meet the nutrient requirements of nearly all healthy people. An AI is an amount of a nutrient thought to be enough and is used when there isn’t enough evidence to identify an RDA.
  • a summary of the data pointing to health benefits of that nutrient. If a condition is not listed, that means there is insufficient evidence to support a connection.
  • recommendations about taking the nutrient in supplement form.
  • a table of selected food sources containing the nutrient, with an emphasis on the best sources in commonly consumed foods.

As a rule, your best strategy is to start by getting vitamins and minerals from foods, not supplements. A vast amount of research has shown that you can cut your risk for chronic disease and disability by following a healthy diet, as well as by exercising regularly, maintaining a healthy weight, and not smoking. The evidence for taking high-dose, individual vitamin and mineral supplements is much less convincing.

Before taking a supplement that delivers more than the recommended daily amount of any nutrient, discuss your decision with your doctor. Your medical history, genetic profile, and medications may affect the dosages and types of supplements you can safely take.

  • Vitamins and minerals: The basics
    • Vitamins vs. minerals
    • Water-soluble vitamins
    • Fat-soluble vitamins
    • Major minerals
    • Trace minerals
  • Cast of characters: From vitamin A to zinc
    • Vitamin A and carotenoids

    • B vitamins

    • Vitamin C

    • Vitamin D

    • Vitamin E

    • Vitamin K

    • Calcium

    • Magnesium

    • Potassium

    • Selenium

    • Zinc

  • Does your diet deliver the daily recommended doses?

    • Decoding your diet

    • Making sense of the nutritional facts panel

    • Making healthy food choices

    • The perks of following a Mediterranean-style diet

  • Supplements: Filling in the gaps
    • Why you might be falling short
    • How to choose safer supplements
    • Should you take a multivitamin?
  • SPECIAL BONUS SECTION: Probiotics, omega-3s, and more
  • Appendix
  • Resources

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