HEALTH TOPICS 
Too much of a good thing?
Proton-pump inhibitors are among the most-prescribed medications, but is long-term use safe?
Proton-pump inhibitors reduce stomach acid, which helps to treat symptoms of acid reflux.
Image: kamontad123/Thinkstock
Proton-pump inhibitors (PPIs), which are used to treat a variety of gastrointestinal problems, are among the most popular drugs in the United States. In fact, the FDA estimates about one in 14 Americans has used a PPI.
To continue reading this article, you must log in.
Subscribe to Harvard Health Online for immediate access to health news and information from Harvard Medical School.
- Research health conditions
- Check your symptoms
- Prepare for a doctor's visit or test
- Find the best treatments and procedures for you
- Explore options for better nutrition and exercise