HEALTH TOPICS 
Too much of a good thing?
Proton-pump inhibitors are among the most-prescribed medications, but is long-term use safe?
Proton-pump inhibitors reduce stomach acid, which helps to treat symptoms of acid reflux.
Image: kamontad123/Thinkstock
Proton-pump inhibitors (PPIs), which are used to treat a variety of gastrointestinal problems, are among the most popular drugs in the United States. In fact, the FDA estimates about one in 14 Americans has used a PPI.
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