Ask Dr. Rob about piriformis syndrome

By , Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

Common condition is the original pain in the buttocks

Piriformis syndrome

What is it?

Piriformis syndrome is a painful condition that develops due to irritation or compression of the sciatic nerve near the piriformis muscle. The piriformis muscle connects the lowermost vertebrae with the upper part of the leg after traveling the "sciatic notch," the opening in the pelvic bone that allows the sciatic nerve to travel into the leg. Here, the muscle and nerve are adjacent and this proximity is why trouble can develop.

The condition is relatively common. Estimates suggest that about 5% of cases of sciatica (irritation of the sciatic nerve causing radiating pain from the back or buttock into the leg, calf and foot) are due to piriformis syndrome. It seems to be more common among women though the reason for this is not known.

Symptoms and signs

The typical patient with piriformis syndrome complains of "sciatica" — that is, sharp, severe, radiating pain from the lower back or buttock down the back of the leg and into the thigh, calf, and foot. Symptoms may seem to be due to hip bursitis or disc herniation ("slipped disc") but the doctor's examination helps sort out the true cause because with piriformis syndrome the person also has:

  • difficulty sitting or putting weight on the buttock on one side
  • muscle spasm of the piriformis muscle
  • pain in the piriformis muscle during a rectal exam
  • sciatica-type pain when the hip is moved and rotated outward against resistance.

Causes of piriformis syndrome

Recognized causes of piriformis syndrome include:

  • Injury
  • Abnormal development or location of the piriformis muscle or sciatic nerve
  • Abnormal spine alignment (such as scoliosis)
  • Leg-length discrepancy (when the legs are of different lengths)
  • Prolonged sitting, especially if carrying a thick wallet in a pocket directly behind the piriformis muscle
  • Prior hip surgery
  • Unusually vigorous exercise
  • Foot problems, including Morton's neuroma.

In many cases the cause cannot be identified.


The diagnosis is "clinical" meaning that it is based on symptoms and physical examination. There is no specific blood test, biopsy, or imaging test to confirm the diagnosis. For this reason, it is difficult to know for sure that a person has the condition and there is some controversy about how common it is. This is especially true because spine and disc disease can cause similar symptoms and piriformis syndrome can be present along with these other conditions such as hip bursitis.

Expected duration

The duration of piriformis syndrome is variable. Often, it is brief in duration, especially if proper treatment begins soon after symptoms appear.


There is no reliable way to prevent piriformis syndrome. For people who have had this or other back problems, standard recommendations include home exercises and stretching, a heel-lift (if the legs are of different lengths), not carrying a wallet in the back pocket, avoiding prolonged sitting, and getting treatment for other contributing conditions (such as spinal arthritis or foot problems). If triggered by vigorous exercise, reducing exercise intensity or changing activities (for example, from running to swimming) can prevent future episodes.


While medications, such as pain relievers, muscle relaxants, and anti-inflammatory drugs may be recommended, the mainstay of treatment for piriformis syndrome is physical therapy, exercise, and stretching. Specific treatments may include:

  • adjustments in gait
  • improved mobility of sacroiliac joints
  • stretching to relieve tight piriformis muscles and those surrounding the hip
  • strengthening of the hip abductors (muscles that move the hips outward from the body)
  • application of heat
  • acupuncture.

If these measures are not effective, more invasive treatment can be considered such as:

  • injections of a local anesthetic (similar to Novocain), botulinum toxin, and/or a corticosteroid agent — these injections are generally guided by ultrasound, x-ray, or electromyogram (which detects muscle and nerve activity) to make sure the needle is in the right place.
  • surgery — Although an option of last resort, removing a portion of the piriformis muscle or its tendon has been reported to provide relief in refractory cases.


With prompt diagnosis and treatment, the prognosis is quite good. However, the condition may become recurrent or chronic; a poor outcome may be more likely if the diagnosis and treatment are delayed.

The bottom line

Piriformis syndrome may be the most common cause of sciatic-type back pain you've never heard of; or it may be rare, no one is really sure. If you have persistent, unexplained buttock pain that travels into the leg, stop carrying your wallet in your back pocket, try not to sit so much, and see your doctor. You might have a disc problem or some other common back trouble; but you could have piriformis syndrome and finding out sooner rather than later can make a difference.


photo of Robert H. Shmerling, MD

Robert H. Shmerling, MD

Senior Faculty Editor, Harvard Health Publishing

Dr. Robert H. Shmerling is the former clinical chief of the division of rheumatology at Beth Israel Deaconess Medical Center (BIDMC) and is a current member of the Corresponding Member of the Faculty of Medicine at Harvard Medical School. As a practicing rheumatologist for over 30 years, Dr. Shmerling engaged in a mix of patient care, teaching, and research. His research interests center on diagnostic studies in patients with musculoskeletal symptoms, and rheumatic and autoimmune diseases. He has published research regarding infectious arthritis, medical ethics, and diagnostic test performance in rheumatic disease. Having retired from patient care in 2019, Dr. Shmerling now works as a senior faculty editor for Harvard Health Publishing.

Twitter: @RobShmerling

To understand why back pain occurs and which treatments are most likely to help, get the Harvard Special Health Report Back Pain: Finding solutions for your aching back.

Image: Eraxion/Getty Images

About the Author

photo of Robert H. Shmerling, MD

Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Robert H. Shmerling is the former clinical chief of the division of rheumatology at Beth Israel Deaconess Medical Center (BIDMC), and is a current member of the corresponding faculty in medicine at Harvard Medical School. … See Full Bio
View all posts by Robert H. Shmerling, MD


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No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

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