Rapaflo approved for the treatment of BPH

Men seeking relief from the symptoms of an enlarged prostate, also called benign prostatic hyperplasia (BPH), now have another treatment option: the FDA approved silodosin (Rapaflo), a once-daily capsule, in October 2008.

As men age, their prostate gland enlarges and presses against the urethra, impeding the flow of urine and making it difficult to eliminate from the body. BPH sufferers may also feel the need to urinate more frequently. By age 50, roughly half of all men suffer from BPH, according to the FDA. By age 80, that number jumps to 75%.

Silodosin falls into a class of medications called alpha-1 blockers. These drugs help muscles in the prostate, bladder, and urethra to relax, allowing urine to flow more easily. Simply put, they deal with the “going” problem. Another class of drugs, called 5-alpha-reductase inhibitors, deals with the “growing” problem by shrinking the prostate.

Not everyone experiences relief with one drug or one type of drug. Men who haven’t responded to other medications may benefit from silodosin.

The most common side effect of silodosin is a lack of semen during orgasm. This does not pose a health or safety problem, and it goes away if the drug is discontinued. Other possible side effects include dizziness, lightheadedness, diarrhea, a drop in blood pressure when standing, headache, and nasal congestion.

For more information about silodosin, talk to your doctor.

Originally published Jan. 1, 2009; Last reviewed April 18, 2011


  1. Barry Mesman

    I tried 1 pill and had severe nasal congestion within 2 hours and diarrhea all the next day. I was sick the 2nd day and the third day I still have nasal congestion which I’m taking cold capsules to alleviate. I wouldn’t recommend this medication to anyone.

  2. Christina

    why not TRY a herbal medicine called Diuretic and Anti-inflammatory Pill, which has no side effect. It’s a patent medicine and has already cured many sufferers with prostate disease

  3. giubbotto alpinestars

    When I unswerving to start a blog earlier this year, I unconditionally had no class how to ordain or what it would take. Bob outlines the maturing from the inception in a plumb calm to see format. I was up and running quicker and more smoothly than if I had tried to do it on my own.

  4. Matthew J.K. Mano

    With all the side effects of this drug why is it continued to be recommended for use. To me these side effects causes more problems then the prostate it self. I believe that there is a cure but then the pharmeceutical companies won’t be making any money for the drugs they sell.As a University i believe that you guys should be finding permanent cures instead of prolong chemical use.

  5. Fernando

    I was quite pleased to get this web-site.I waentd to thanks for your time for this terrific read!! I absolutely enjoying every little bit of it and I have you bookmarked to have a look at new stuff you blog post.

Commenting has been closed for this post.