HEALTH TOPICS 
Granulomatosis with polyangiitis
What Is It?
Granulomatosis with polyangiitis (GPA) is a rare disease marked by inflammation of the blood vessels. The condition is potentially life-threatening. It was formerly called Wegener's granulomatosis.
In GPA, inflammation damages the walls of small- and medium-sized arteries and veins. This damage interferes with normal blood supply to nearby tissues. As a result, tissues in many parts of the body may be injured and destroyed.
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