Harvard Health Letter

By the way, doctor: How much Imitrex is too much?

Q. My doctor suggested switching to a low-dose antidepressant like Elavil to take prophylactically rather than taking too much Imitrex, but I don't remember what the "too much" cutoff amount is.

A. Sumatriptan (Imitrex) is one of the increasingly popular triptan drugs that people take for migraine headaches. The triptans both constrict vessels in the head and inhibit pain signals traveling to the brain. It's unclear which of these mechanisms is most important in stifling migraine pain.

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