Prostate Knowledge Archive

How one man persisted for almost two years in an effort to remedy one of the most bothersome possible side effects of prostate cancer treatment, and what men facing therapeutic decisions can learn from his experience.

When cancer advances despite primary hormone therapy

We often hear the term prostate cancer and assume it is one disease. Practically speaking, it is. On a molecular level, however, scientists are revealing a far more complex picture. Cancer has an innate ability to adapt to its surroundings. As it progresses, cancer cells tend to change, morphing to a point where the differences between tumor cells can be dramatic. That’s why some researchers believe late-stage prostate cancer is more accurately described as a mix of cancer cell types.

An interview with renowned urology researcher E. David Crawford, M.D., about the state of clinical trials on prostate health

Can hormone therapy extend the lives of men with advanced prostate cancer? Might a drug traditionally prescribed to treat benign prostatic hyperplasia (BPH) help prevent prostate cancer? Does a short course of hormone therapy prior to a radical prostatectomy prevent or delay cancer’s return?

Marc B. Garnick, M.D., provides an overview of possible treatments that need more study, including cryotherapy, HIFU, and focal therapies.

Marc B. Garnick, M.D., discusses what biochemical recurrence means and what your options are.

Three Harvard-affiliated physicians discuss the impact that hormone therapy can have on bones and cardiovascular health.

Marc B. Garnick, M.D., discusses this therapy, which aims to strike a balance between effective treatment and quality of life.

Marc Garnick, M.D., Editor in Chief of the Annual Report on Prostate Diseases, discusses what you need to know about therapy: when it’s used, what your options are, and what doctors disagree about.

Which men are candidates for active surveillance? Some studies suggest that men with low risk cancer should consider active surveillance over traditional treatment, but the evidence is mixed.

When it comes to early-stage prostate cancer, there is no evidence that one treatment is better than another or that any treatment at all actually prolongs life. If you are diagnosed with early-stage prostate cancer, you’ll want to consider factors such as your values, your quality of life, and the potential side effects of various treatments before making a decision.