Identifying prediabetes may present opportunity to reduce heart disease risk

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Published: October, 2020

People with prediabetes — a condition in which blood sugar is elevated but not high enough to be considered diabetes — often go undiagnosed. That may put them at higher risk of cardiovascular disease and even early death, according to an analysis of 129 studies published in the July 18, 2020, issue of The BMJ.

The analysis, which combined data on some 10 million people, found that prediabetes raised the risk of dying from cardiovascular disease by 15% and from any cause by 13% over a median follow-up period of about 10 years. The mortality risk was even higher in people with prediabetes who also had coronary artery disease: they had nearly a 40% increased risk of dying within a median follow-up period of just three years. The study authors suggest that finding and addressing more cases of prediabetes could lead to a lower risk of future cardiovascular disease.

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