By the way, doctor: Should I switch from tamoxifen to an aromatase inhibitor?
Tamoxifen works by attaching to estrogen receptors in breast tissue and blocking the hormone's effects. In other tissues, it mimics estrogen, which can have both good and bad effects. On the positive side, tamoxifen stimulates bone growth, reducing the risk of osteoporosis. But in the uterus, it stimulates the growth of endometrial tissue, increasing the risk of endometrial cancer. It also raises the risk of serious, sometimes fatal, blood clots. Tamoxifen is not recommended for more than five years.
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