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Harvard Health Blog
World Stroke Day: stroke is common, disabling, and often preventable
- By: Howard E. LeWine, MD,
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What would probably make even more sense would be to prevent the neuronal cascade of death in the first week. Less dead and damaged neurons would directly result in better recoveries. Dr. Michael Tymianski, of the Toronto Western Hospital Research Institute in Canada mentions 1000 failed drugs that worked in rodents but failed in human trials. These probably need to be looked at again since it has now been proven that rodent inflammation is not the same as human inflammation. In my next stroke I have 31 possibilities that I will insist my doctor provide to me. Things like;
blood pressure cuffs in the ambulance ride
2. Fish oil.
either by injection
or a feeding tube
3. Leg compressions
4. anti-depressants – real ones
5. music listening
6. Sensation overload
7. Coffee –
9. Peptide application
10. Action observation
11. bFGF administered intravenously
12. Viagra –
13. Training in lucid dreaming.
15. dietary olive leaf extract
16. ebselen – neuroprotective treatment? within 48 hours
17. diabetes drug linagliptin
18. Etazolate, an α-secretase activator
19. Glibenclamide – administered intravenously 6, 12, and 24 hours after reperfusion
20. Paeoniflorin (PF) – PF treatment for 14 days
21. administration of nontoxic carbon particles
23. Ceria nanoparticles
24. Head-of-Bed Optimization of Elevation
25. antibiotic minocycline
26. neurotransmitter precursor levodopa
27. Inhalation of nitric oxide
28. old flu drug amantadine
30. opiate antagonists
All these have some research already backing them even if they have not been in human clinical trials. Its worth it to my brain to take some chances to save my neurons from dying from glutamate poisoning, excitotoxicity,Capillaries that don’t open due to pericytes, Inflammatory action leaking through the blood brain barrier.
You didn’t mention the specific preventions ideas of
Potassium 21% Why eat three bananas a day?
Marijuana buds 50% A Marijuana Bud A Day Keeps The Stroke Away
Dietary magnesium 8% Higher magnesium intake associated with reduced ischemic stroke risk
Mediterranean diet 30% – Mediterranean Diet Proven Key In Avoiding Heart Disease And Stroke
lycopene – tomatoes 55% -Tomatoes Linked to Lower Stroke Risk
Fish 6% – Does Eating Two Fish a Day REALLY Keep the Chance of Stroke Away?
Chocolate eating 17% Eating small bar of chocolate cuts risks of stroke in men
Walking 43% – Walking wards off stroke for women
Speed walking 50% – Speed Walking Halves Stroke Risk
Dietary fiber 7% –
The generic prevention ideas are not really listened to.
Great comments Dean. As a neurologist is the SE US i.e. the stroke belt who takes “stroke call” and a fellow in Integrative medicine I think you have pretty much identified the issues and the solutions .
I applaud Dr. LeWine for his excellent efforts in bringing the issues of stroke in the young to light. But I think we have failed miserably as a profession to leverage the benefits of interventions such as the Mediteranean diet in prevention of stroke.
I don’t know about cannabis…but…after seeing Sanjay Gupta’s CNN documentary “Weed” and reading the review of cannabis in the Weil Integrative Oncology book I believe that the endocannabinoid system is an overlooked potential source for the relief of human suffering.
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