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- By: John Ross, MD, FIDSA, Contributing Editor
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At this moment I am going away to do my breakfast, after having my breakfast coming again to read
This article you have is so wonderful. i feel like you have explained all about flu or influenza
I read your article, it is very helpful and I got information about flu or influenza vaccine and I will take in future during a flu season.
Hi Syed! I would say that statins probably do not either cause or protect against dementia. The best data on statins and dementia risk comes from the Heart Protection Study (HPS) and the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). These two double-blind trials looked at cognitive function over several years in over 26,000 high-risk patients taking either statin or placebo. Basically, they were a wash. The incidence of dementia was the same in the statin group and the placebo group in both studies. Compared to the placebo group, all-cause mortality was lower in the statin group in HPS (which used simvastatin) but was unchanged in the statin group in PROSPER (which used pravastatin).
For a comprehensive, if dense, review of this topic, check out: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458855/
A little rationality lifts the quality of the debate here. Thanks for coiiunbrttng!
Very interesting article. Statins are also implicated in memory loss and dementia?
Probably not. The best data on this comes from the Heart Protection Study and the Prospective Study of Pravastatin in the Elderly at Risk. These randomized, double-blind studies looked at cognitive function over several years in over 26,000 high risk patients taking either placebo or statin. The risk of dementia was the same in both groups.
For a comprehensive review, check out: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458855/
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