Harvard Heart Letter

Heart Beat: Take aspirin before ibuprofen, not after

Heart Beat

Take aspirin before ibuprofen, not after

If you take aspirin for your heart and ibuprofen for your aches and pains, try to take the aspirin first each day. That's what the FDA is recommending in a warning to consumers and health care professionals.

In 2003 we highlighted research suggesting that ibuprofen (Motrin, Advil, others) could block the heart-protecting action of aspirin. Subsequent work supporting this idea prompted the FDA to issue its warning in mid-September 2006.

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