Caution Urged on Testosterone Therapy

Published: April, 2004

Boston , MA — About a million men are turning to testosterone therapy in hopes of restoring vitality and slowing the aging process. Boosting testosterone makes sense for men with low hormone levels. But for men with normal levels, little is known about the long-term effects of testosterone therapy on the heart, blood vessels, and other parts of the body.

By age 60, about one in five men have testosterone levels lower than what's normal for younger men, though no one knows if these levels are low for men their age. According to the April Harvard Heart Letter , this is just one of many things that needs to be discovered about the effects of testosterone therapy on men's health. One gray area is how daily doses of the hormone affect the heart, blood vessels, and circulation. Some studies suggest that testosterone can lower blood pressure, increase levels of HDL (good) cholesterol, and decrease the chances of developing atherosclerosis or diabetes. If this paints a positive, why-not-start-today picture of testosterone therapy, the recent flip-flop on postmenopausal hormone therapy in women should raise a red flag.

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