Heart Beat: Trial Watch

Heart Beat

Trial Watch

Published: October, 2009

Welcome to the first installment of Trial Watch. In this occasional feature, we will highlight important nationwide clinical trials that are in need of participants.

CLEVER. The Claudication: Exercise Versus Endoluminal Revascularization Study is tackling a key question that could help some of the millions of people with peripheral artery disease: What is the best way to treat leg pain that occurs with walking (a condition known as claudication)? There are currently three main options for those afflicted by this aggravating and sometimes disabling condition. These include exercise at home plus drug therapy, supervised exercise therapy plus drug therapy, and placement of an artery-opening stent. In CLEVER, volunteers with claudication will be randomly assigned to one of these three options or a fourth one — stent placement plus supervised exercise and drug therapy. The researchers will measure the effectiveness, safety, cost, and overall economic impact of the four strategies. The trial is being conducted at 30 hospitals across the country.

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