In Brief: More evidence that varenicline harms the heart
Varenicline (Chantix) is one of the most common drugs prescribed for people who want to stop smoking. But evidence is growing that it may harm the heart.
In June 2011, the FDA warned people with heart disease that varenicline could slightly raise risk of heart attacks and other cardiac events, and asked the drug's manufacturer to add a warning label to that effect. In July 2011, a meta-analysis that reviewed results from 14 randomized controlled studies provided information about how to better understand the risks and benefits of varenicline.