Medical memo: Autoantibody signatures: A promising new test for prostate cancer
Medical memo
Autoantibody signatures: A promising new test for prostate cancer
Modern medicine has made great strides in the fight against cancer, especially in finding improved ways to diagnose the disease. Not too long ago, many malignancies were diagnosed only after they grew large enough to make people seriously ill or produce a lump or mass that doctors could feel. Next, x-rays were used to detect smaller tumors, and now nuclear scans, CT scans, and MRIs can diagnose much smaller, earlier growths. But as good as they are, these tools are not always good enough, so scientists are turning to biomarkers for even earlier diagnosis.
The prostate-specific antigen (PSA) is a biomarker, a protein produced by prostate cancer cells that can be detected and measured in a man's blood. PSA testing is currently the best way to detect prostate cancer, but it's imperfect. Part of its limitation stems from the fact that all prostate cells, benign and malignant, produce PSA. So while men with prostate cancer tend to have higher blood PSA levels than men without the disease, there is considerable overlap, resulting in many false-positive and false-negative results.
To continue reading this article, you must log in.
Subscribe to Harvard Health Online for immediate access to health news and information from Harvard Medical School.
- Research health conditions
- Check your symptoms
- Prepare for a doctor's visit or test
- Find the best treatments and procedures for you
- Explore options for better nutrition and exercise
I'd like to receive access to Harvard Health Online for only $4.99 a month.
Sign Me UpAlready a member? Login ».
Disclaimer:
As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles.
No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.