Recent Blog Articles
5 inflammation-fighting food swaps
Is IBD an underrecognized health problem in minority groups?
Sickle cell disease in newborns and children: What families should know and do
COVID-19 vaccines for children and teens: What we do — and don’t — know
Happy trails: Take a hike, now
Sleep well — and reduce your risk of dementia and death
COVID-19 vaccines and the LGBTQ+ community
Polycystic ovary syndrome and the skin
Dental appliances for sleep apnea: Do they work?
Terrified of needles? That can affect your health
In the News: Heart failure risk prompts warning labels on diabetes drugs
In the News
Heart failure risk prompts warning labels on diabetes drugs
The concern now is whether this particular class of drugs causes other cardiovascular problems.
In May 2007, the FDA told the makers of two diabetes drugs to add "black box" warnings to their labels because of the risk of heart failure. Both medications — Avandia (rosiglitazone), marketed by GlaxoSmithKline, and Actos (pioglitazone), by Takeda Pharmaceuticals — are thiazolidinediones. This class of drugs lowers blood sugar by increasing insulin sensitivity in liver and muscle cells. Insulin is the hormone that moves sugar from the blood into cells. The FDA announced the call for labeling revisions during a Congressional hearing on reports linking Avandia to heart attacks and cardiovascular death.
To continue reading this article, you must log in.
Subscribe to Harvard Health Online for immediate access to health news and information from Harvard Medical School.
- Research health conditions
- Check your symptoms
- Prepare for a doctor's visit or test
- Find the best treatments and procedures for you
- Explore options for better nutrition and exercise
I'd like to receive access to Harvard Health Online for only $4.99 a month.
Sign Me UpAlready a member? Login ».
Disclaimer:
As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.