In Brief: Schizophrenia and bipolar disorder may share genetic origins
A long-running debate in psychiatry is whether schizophrenia and bipolar disorder are really two distinct illnesses, or instead represent different manifestations of a single mental illness. A large study provides evidence that, however they are classified, schizophrenia and bipolar disorder are more alike genetically than they are different.
Investigators at the Karolinska Institute examined two national registry databases in Sweden, which included information about family psychiatric histories of 9 million people from 1973 to 2004. They identified 35,985 individuals with hospital discharge diagnoses of schizophrenia and 40,487 with bipolar disorder. The researchers excluded patients with schizoaffective disorder, a separate condition that shares symptoms of both illnesses.
Subscribe to Harvard Health Online for immediate access to health news and information from Harvard Medical School.
- Research health conditions
- Check your symptoms
- Prepare for a doctor's visit or test
- Find the best treatments and procedures for you
- Explore options for better nutrition and exercise
New subscriptions to Harvard Health Online are temporarily unavailable. Click the button below to learn about our other subscription offers.