Depression at perimenopause: More than just hormones

A new study is helping to untangle the many contributors to depression during the menopausal transition.

New research has confirmed a link between depression and the menopausal transition, or perimenopause — that time of erratic periods, chaotic hormone fluctuations, disturbed sleep, and, for some, uncomfortable hot flashes. Researchers don't understand all the "whys" yet, but a Seattle-based study should help. Among the findings: little or no correlation between hormone levels and depression during perimenopause. However, a host of other factors have been implicated.