Obesity raises heart disease risk despite healthy metabolic profile

Published: July, 2014

Is there such a thing as metabolically healthy obesity, also known as being "fit but fat"? Not when it comes to coronary artery disease, say the authors of an article in the Journal of the American College of Cardiology.

Using computed tomography (CT), the researchers examined the coronary arteries of 14,828 middle-aged men and women for microscopic calcium deposits, an early indicator of atherosclerosis. None of the participants had known cardiovascular disease, and all were deemed to be metabolically healthy. Metabolic health was defined as having normal cholesterol, blood pressure, and blood sugar levels as well as no evidence of insulin resistance.

To continue reading this article, you must log in.
  • Research health conditions
  • Check your symptoms
  • Prepare for a doctor's visit or test
  • Find the best treatments and procedures for you
  • Explore options for better nutrition and exercise

New subscriptions to Harvard Health Online are temporarily unavailable. Click the button below to learn about our other subscription offers.

Learn More »