A direct drug hit with alteplase busts up leg clots
Catheters — thin plastic tubes that doctors route through the body's arteries and veins — can carry everything from tiny cameras to replacement heart valves. So why not clot-busting drugs?
That was the idea behind a Norwegian study that looked at nearly 200 people who had a blood clot in a leg vein (deep-vein thrombosis, or DVT). People with DVT usually take a blood thinner like warfarin to prevent the clot from growing and to stop new ones from forming. These drugs also keep the clot from fragmenting and traveling to the lungs — a potentially life-threatening complication known as a pulmonary embolism.
Subscribe to Harvard Health Online for immediate access to health news and information from Harvard Medical School.
- Research health conditions
- Check your symptoms
- Prepare for a doctor's visit or test
- Find the best treatments and procedures for you
- Explore options for better nutrition and exercise