What Is It?
Polyarteritis nodosa is a rare, but potentially life threatening, inflammation of the blood vessels (vasculitis) that damages the walls of the body's small- and medium-sized arteries. This damage slows the supply of blood and nourishment to the arteries, causing nearby tissue in many parts of the body to be injured or even destroyed. The disease most commonly affects the kidneys, the nerves of the arms and legs and the abdominal organs, although it can also involve the skin, joints, muscles, brain, heart, eyes and reproductive organs.
In individual organs, polyarteritis nodosa can have the following effects: