Autoimmune diseases

Stem-cell transplant: A possible high-risk/high-reward treatment for scleroderma

Robert H. Shmerling, MD

Faculty Editor, Harvard Health Publishing

Scleroderma is a painful, potentially debilitating autoimmune disease without good treatments. A novel approach to treating severe scleroderma using stem-cell transplantation to “reboot” the immune system shows great promise but not without potentially serious side effects.