Alzheimer’s Disease

Trouble with crossword puzzles? Improve your semantic memory

Semantic memory is your store of factual knowledge and the meanings of words. It also helps you recall nonverbal concepts and relationships between words and concepts. And while some aspects of memory may decline with age, semantic memory does not.

A clue to a cure for Alzheimer’s disease

Half of people who live to 85 will develop Alzheimer’s disease — a disturbing statistic. But research into a family in South America has revealed a gene mutation that appears to afford protection, and may lead to a way to treat or possibly even prevent the disease.

Is there a test for Alzheimer’s disease?

Wondering whether a blood test or brain scan can accurately diagnose Alzheimer’s disease? If memory loss is a problem for you or a loved one, consider these points before discussing potential next steps with a doctor.

A poor sense of smell might matter more than you thought

Robert H. Shmerling, MD

Faculty Editor, Harvard Health Publishing

Loss of the sense of smell affects quality of life and possibly safety, but it can also be a sign of a more serious illness. Researchers found that elderly people with a poor sense of smell were more likely to have certain illnesses, and more likely to die of them.

Brain health rests on heart health: Guidelines for lifestyle changes

Monique Tello, MD, MPH

Contributing Editor

The World Health Organization has issued prevention guidelines for preventing dementia. Of note, the guidelines are very similar to those for heart health, reinforcing the known connections between heart health and brain health.

Can an eye exam reveal Alzheimer’s risk?

New research considers whether certain eye conditions may help predict Alzheimer’s disease. The common link? Cardiovascular disease, which is partly preventable.

Intensive treatment of blood pressure helps prevent memory decline in older adults

Gad Marshall, MD

Contributor

The results of a study on cardiovascular health and memory found that people who received intensive treatment to lower their blood pressure were significantly less likely to develop mild cognitive impairment.

Could medications contribute to dementia?

Robert H. Shmerling, MD

Faculty Editor, Harvard Health Publishing

A study found that people over 65 who were taking an anticholinergic medication (drugs that block the chemical messenger acetylcholine) were more likely to eventually be diagnosed with dementia, but these results don’t show that this class of drugs definitively causes dementia.

New study downplays potential risk of dementia and Alzheimer’s disease among elderly men treated with hormonal therapy for prostate cancer

Charlie Schmidt

Editor, Harvard Medical School Annual Report on Prostate Diseases

The male hormone testosterone contributes to normal brain function, and some research links memory loss in older men to testosterone declines that occur naturally with aging. However, testosterone is also like jet fuel for prostate tumors, causing them to grow faster, so during cancer treatment doctors will often give hormonal therapies that suppress its activities […]

Can getting quality sleep help prevent Alzheimer’s disease?

Matthew Solan

Executive Editor, Harvard Men's Health Watch

Sleep gives the brain the opportunity to rid itself of proteins believed to contribute to the development of Alzheimer’s disease, and now research is showing an association between poor sleep and the accumulation of those proteins.