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C. difficile symptoms: Antibiotics and C. difficile bacterium

BOSTON — Illness related to C. difficile, a bacterium commonly found in hospitals, is becoming more widespread, more severe, and harder to treat, reports the April 2007 issue of Harvard Women’s Health Watch. Health experts are worried that a new, more virulent strain may be to blame.

Antibiotics and C. difficile Bacterium

Certain strains of C. difficile produce toxins that attack the cells lining the colon. Those strains can cause symptoms ranging from mild diarrhea to severe colitis if they enter the gastrointestinal tract of a person who is taking antibiotics. Although antibiotics kill off many types of harmful bacteria, they can also wipe out the good bugs in the large intestine that keep C. difficile in check.

Most people exposed to C. difficile will not get sick from it, nor will most people who take antibiotics. The risk is higher for patients who are older, spend more time in the hospital, and are treated for a longer period with antibiotics. You can help limit the spread if you learn the risk factors and take some precautions. The Harvard Women’s Health Watch recommends these steps:

  • Wash your hands thoroughly after visiting a hospital.
  • Use soap and water; alcohol-based hand gels do not kill C. difficile. If you’ve been taking antibiotics and you develop watery diarrhea and abdominal pain, see your clinician right away.
  • Take antibiotics exactly as prescribed. They are of no use in treating colds and other viral diseases.
  • Sometimes you need to be in a hospital. But as soon as you feel well enough, ask if home health care is an option for you.

Also in this issue of the Harvard Women's Health Watch

  • A better way to predict cardiovascular risk
  • In Brief: Cognitive behavioral therapy helps ease tinnitus discomforts
  • In Brief: Even mildly impaired kidney function can affect bone health
  • What to do about tennis elbow
  • Sunscreens: New wave in sun protection: Blocking ultraviolet A
  • C. difficile-associated disease on the rise
  • By the way, doctor: How often do I need a bone density test?

More Harvard Health News »


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Harvard Health Publications publishes four monthly newsletters--Harvard Health Letter, Harvard Women's Health Watch, Harvard Men's Health Watch, and Harvard Heart Letter--as well as more than 50 special health reports and books drawing on the expertise of the 8,000 faculty physicians at Harvard Medical School and its world-famous affiliated hospitals.