Harvard Perspectives on Prostate Disease

Hormone therapy for prostate cancer

Editor in Chief Marc B. Garnick, M.D.,* discusses the options and controversies

*Disclosure "" Dr. Garnick is currently serving as a consultant to SpecialtyEuropeanPharma, which is developing abarelix in Europe.

Androgens, the family of male sex hormones that includes testosterone, function as a fuel for growth "" a quality that explains their central role in both normal development and prostate cancer. In adolescent boys, androgens not only trigger sexual development, but also contribute to a deeper voice, a beard, and increased muscle strength and bone mass. When prostate cancer develops, however, this androgen fuel contributes to tumor growth and progression.

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