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Stanek EJ, Aubert RE, Flockhart DA, et al. A national study of
the effect of individual proton pump inhibitors on cardiovascular
outcomes in patients treated with clopidogrel following coronary
stenting: The Clopidogrel Medco Outcomes Study. Society for
Cardiovascular Angiography and Interventions annual
meeting, presented May 6, 2009.
Bhatt DL, Scheiman J, Abraham NS, et al. ACCF/ACG/AHA 2008 expert
consensus document on reducing the gastrointestinal risks of
antiplatelet therapy and NSAID use: a report of the American
College of Cardiology Foundation Task Force on Clinical Expert
Consensus Documents. Journal
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Statement on "A National Study of the Effect of Individual Proton
Pump Inhibitors on Cardiovascular Outcomes in Patients Treated
with Clopidogrel Following Coronary Stenting: The Clopidogrel
Medco Outcomes Study". Society for
Cardiovascular Angiography and Interventions, Washington DC,
May 6, 2009.
Strokes without a known cause are called cryptogenic strokes. One
possible cause of these is a hole in the wall separating the
right atrium from the left. Whether fixing this opening, called a
patent foramen ovale (PAY-tent foe-RAY-men oh-VAH-lee, PFO)
prevents such strokes has yet to be determined. It's possible
we'll never have an answer because some doctors, researchers, and
stroke victims seem to be convinced that closing a PFO is good
medicine. That's why the American Heart Association, American
Stroke Association, and American College of Cardiology are urging
doctors to enroll
patients with cryptogenic stroke in one of the ongoing trials
testing the benefits and risks of PFO closure.
These trials include:
GORE HELEXTM Septal Occluder for Patent Foramen
Ovale Closure in Stroke Patients (Gore
REDUCE) in the United States
Many people who take aspirin and clopidogrel (Plavix) to prevent
blood clots also take a proton-pump inhibitor (PPI) to ease the
gastrointestinal bleeding the other medications can cause. But a
study found that PPIs can limit the effectiveness of Plavix.
Stroke victims are more likely to have a patent foramen ovale, a
hole between the heart's left and right atria, but closing the
hole may not prevent the occurrence of another stroke.
Adding fruits and vegetables to your diet is a simple way to eat more healthfully. Here are some suggestions to make healthy eating more fun and interesting.
Fainting occurs when blood flow to the brain is blocked or interrupted. An incident of fainting should be reported to a doctor, because if it was caused by a problem in the heart, it may lead to more serious problems.
Readers suggest alternative terms for a transient ischemic
Everyone wants to live longer, and there are many preventable
causes of death that can be avoided with proper health habits.
When someone has a stroke, immediate treatment is essential. The
American Stroke Association says a clot-destroying drug called
tPA may work for up to four and a half hours after the onset of a
stroke, but should be given within an hour if possible.
Brief reports on CPR and an improved cardiac arrest survival
rate, chewable aspirin as a rapid heart attack aid, and the
effect of lack of sleep on blood pressure.
Long ago I was told that isometric exercises, like weight
lifting, shouldn't be done by anyone with a heart condition. Is
that still the prevailing wisdom?
What are silent heart attacks? How are they different from
regular ones? If they are silent, how does anyone know about
I work out regularly six times a week, but suffer from
exercise-induced angina and what my doctor calls a vascular
problem. If I start exercising without first warming up, my chest
starts to feel “tight” before I’ve walked 100 yards. The same
thing happens if I start walking after being seated for a while,
such as when I walk to the baggage claim area to get my luggage
after getting off a plane. If I warm up properly, though, I can
walk for several miles at a pretty fast pace without any chest
pain. Can you explain what is going on?
I am an 82-year-old man with borderline leakage in my mitral
valve. Your article on mitral valve prolapse said, “The operation
to repair or replace a leaky mitral valve is big enough that you
don’t want to undergo it unnecessarily, but important enough that
you don’t want to wait until symptoms develop.” What symptoms or
tests would help me and others recognize when it is time to
consider having the valve fixed?