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References for "Failed efforts to thwart Alzheimer's disease raise questions"

FEB 2009

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Aisen PS, et al. “High-dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease: A Randomized Controlled Trial,” Journal of the American Medical Association (Oct. 15, 2008): Vol. 300, No. 15, pp. 1774–83. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18854539

Atri A, et al. “Long-term Course and Effectiveness of Combination Therapy in Alzheimer Disease,” Alzheimer Disease and Associated Disorders (July–Sept., 2008): Vol. 22, No. 3, pp. 209–21. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18580597

Arvanitakis Z, et al. “Statins, Incident Alzheimer Disease, Change in Cognitive Function, and Neuropathology,” Neurology (May 6, 2008): Vol. 70, No. 19, pt. 2, pp. 1795–802. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18199831

Balk EM, et al. “Vitamin B6, B12, and Folic Acid Supplementation and Cognitive Function: A Systematic Review of Randomized Trials,” Archives of Internal Medicine (Jan. 8, 2007): Vol. 167, No. 1, pp. 21–30. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17210874

Buchman AS, et al. “Total Daily Activity is Associated with Cognition in Older Persons,” American Journal of Geriatric Psychiatry (Aug. 2008): Vol. 16, No. 8, pp. 697–701. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18669949

Clarke RJ, et al. “B Vitamins for Prevention of Cognitive Decline: Insufficient Evidence to Justify Treatment,” Journal of the American Medical Association (Oct. 15, 2008): Vol. 300, No. 15, pp. 1819–21. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18854547

Cramer C, et al. “Use of Statins and Incidence of Dementia and Cognitive Impairment Without Dementia in a Cohort Study,” Neurology (July 29, 2008): Vol. 71, No. 5, pp. 344–50. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18663180

DeKosky ST, et al. “Ginkgo Biloba for Prevention of Dementia,” Journal of the American Medical Association (Nov. 19, 2008): Vol. 300, No. 19, pp. 2253–62.

Holmes C, et al. “Long-Term Effects of Abeta42 Immunization in Alzheimer’s Disease: Follow-Up of a Randomized, Placebo-Controlled Phase I Trial,” Lancet (July 19, 2008): Vol. 372, No. 9634, pp. 216–23. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18640458

Lautenschlager NT, et al. “Effect of Physical Activity on Cognitive Function in Older Adults at Risk for Alzheimer Disease: A Randomized Trial,” Journal of the American Medical Association (Sept. 3, 2008): Vol. 300, No. 9, pp. 1027–37. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18768414

Petersen RC, et al. “Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment,” New England Journal of Medicine (June 9, 2005): Vol. 352, No. 23, pp. 2379–88. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15829527

Roe CM, et al. “Alzheimer Disease and Cognitive Reserve: Variation of Education Effect with Carbon 11–Labeled Pittsburgh Compound B Uptake,” Archives of Neurology (Nov. 2008): Vol. 65, No. 11, pp. 1467–71. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19001165

Selkoe DJ. “Biochemistry and Molecular Biology of Amyloid Beta-Protein and the Mechanism of Alzheimer’s Disease,” in Duyckaerts C, et al., eds. Handbook of Clinical Neurology, Vol. 89 (3rd series, Elsevier, 2008).

Shankar GM, et al. “Amyloid-Beta Protein Dimers Isolated Directly From Alzheimer’s Brains Impair Synaptic Plasticity and Memory,” Nature Medicine (Aug. 2008): Vol. 14, No. 8, pp. 837–42. www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18568035