Harvard Mental Health Letter

Using lithium to reduce suicide risk in bipolar disorder

Why lithium is the best medication option, and how to make it work better.

As the treatment arsenal for bipolar (manic-depressive) disorder has expanded in recent years, some experts have become concerned that lithium — a mainstay of treatment since FDA approval in 1970 and still considered the most effective option for long-term therapy — may be falling out of favor.

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