Harvard Heart Letter

Plavix isn't for everyone

Adding Plavix to aspirin doesn't help people without heart disease.

There are several good reasons to fortify aspirin's anti-clotting action with the "superaspirin" Plavix (clopidogrel). Having stable heart disease or being at high risk for developing heart disease, it turns out, aren't among them. Surprising results from a trial that included more than 15,000 volunteers showed that aspirin alone is safer and just as effective as aspirin plus Plavix at preventing heart attack, stroke, and other cardiovascular problems in these groups.

These findings don't diminish the benefits of Plavix plus aspirin, or Plavix alone, in some situations. It remains an important treatment for people

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