Calf or thigh pain while walking that goes away with rest is the hallmark of peripheral artery disease. Although often dismissed as a back or hip problem, it can be the first indication of blocked or narrowed arteries throughout the body. Such problems in the legs usually indicate similar problems elsewhere in the body. Treating peripheral artery disease focuses on relieving leg pain and reducing the chances of having a heart attack or stroke. The best medicine for leg pain is a program of regular walking. Cardiovascular risks are addressed with a combination of lifestyle changes and medicines to control high blood pressure, diabetes, and cholesterol.
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