Harvard Heart Letter

Digoxin: Old friend or old foe?

Digoxin is among the oldest cardiac drugs still in use, but its history has been marked by controversy. The higher doses needed to achieve the desired therapeutic effect could escalate to toxicity and cause sudden death. However, better understanding of how the drug works has led to a potential new role for digoxin in improving quality of life and reducing hospital stays for people with advanced heart failure.
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