Multiple Myeloma

Questions to Discuss with Your Doctor:

• Have you had any recent infections?
• Do you have a cough?
• Do you have sinus congestion?
• Do you have burning with urination?
• Do you know when to call your doctor with symptoms of infection?
• Do you have pain in any of your bones? If so, is it constant, or does it occur only when you move?
• Have you had any recent fractures?
• Do you have pain in your spine? Does it radiate to another part of your body?
• Have you noticed a decrease in sensation or strength in your hands or feet?
• Have you had loss of bladder or bowel control?
• Do you know when to seek medical attention for back pain?
• Have you been fatigued?
• Have you been lightheaded?
• Have you been short of breath with minimal exertion?
• Do your gums bleed when you brush your teeth?
• Do you bruise easily, or get nosebleeds?
• Have you been weak, nauseated, constipated, or confused?
• Have you had a headache or a change in your vision?
• Can you feel any lumps or masses under your skin?
• Are you aware of the possible complications that can develop from multiple myeloma?
• Do you know which symptoms should cause you to call your doctor?

Your Doctor Might Examine the Following Body Structures or Functions:

• Heart
• Lungs
• Bones
• Neurology examination (to check for strength and sensation in your hands and feet)
• Skin
• Lymph nodes (neck, axilla, and groin)

Your Doctor Might Order the Following Lab Tests or Studies:

• Blood tests for complete blood count, electrolytes, kidney function, uric acid, calcium, and beta-2 microglobulin (see p. 153)
• Serum protein electrophoresis or SPEP (see p. 157)
• Urine protein electrophoresis or UPEP
• Quantitative immunoglobulin levels in the urine and blood
• Immunoelectrophoresis
• 24-hour urine collection for protein
• Bone marrow biopsy (see p. 720)
• Skeletal radiographs
• CT scan (see p. 141)
• MRI scan (see p. 143)