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Multiple Myeloma

Questions to Discuss with Your Doctor:

  • Have you had any recent infections?
  • Do you have a cough?
  • Do you have sinus congestion?
  • Do you have burning with urination?
  • Do you know when to call your doctor with symptoms of infection?
  • Do you have pain in any of your bones? If so, is it constant, or does it occur only when you move?
  • Have you had any recent fractures?
  • Do you have pain in your spine? Does it radiate to another part of your body?
  • Have you noticed a decrease in sensation or strength in your hands or feet?
  • Have you had loss of bladder or bowel control?
  • Do you know when to seek medical attention for back pain?
  • Have you been fatigued?
  • Have you been lightheaded?
  • Have you been short of breath with minimal exertion?
  • Do your gums bleed when you brush your teeth?
  • Do you bruise easily, or get nosebleeds?
  • Have you been weak, nauseated, constipated, or confused?
  • Have you had a headache or a change in your vision?
  • Can you feel any lumps or masses under your skin?
  • Are you aware of the possible complications that can develop from multiple myeloma?
  • Do you know which symptoms should cause you to call your doctor?

Your Doctor Might Examine the Following Body Structures or Functions:

  • Heart
  • Lungs
  • Bones
  • Neurology examination (to check for strength and sensation in your hands and feet)
  • Skin
  • Lymph nodes (neck, axilla, and groin)

Your Doctor Might Order the Following Lab Tests or Studies:

  • Blood tests for complete blood count, electrolytes, kidney function, uric acid, calcium, and beta-2 microglobulin (see p. 153)
  • Serum protein electrophoresis or SPEP (see p. 157)
  • Urine protein electrophoresis or UPEP
  • Quantitative immunoglobulin levels in the urine and blood
  • Immunoelectrophoresis
  • 24-hour urine collection for protein
  • Bone marrow biopsy (see p. 720)
  • Skeletal radiographs
  • CT scan (see p. 141)
  • MRI scan (see p. 143)


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