Lymph Node Biopsy
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What is the test?
Lymph nodes are small
balls of tissue that are part of the body's immune system. The
nodes produce and harbor infection-fighting white blood cells
(lymphocytes) that attack both infectious agents and cancer cells.
Cancer, infection, and some other diseases can change the appearance
of lymph nodes. For that reason, your doctor may ask a surgeon
to remove lymph nodes, to be examined microscopically for evidence
of these problems.
Usually, one or more
entire lymph nodes are removed and examined under the microscope
by a pathologist. On occasion, the doctor does a needle biopsy
to remove a portion of a lymph node to see whether a cancer already
diagnosed has spread to that point.
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How do I prepare
for the test?
Tell your doctor if
you're allergic to any medications, if you're taking NSAIDs or
any medications that might cause bleeding, if you have a condition
that bleeds easily such as an ulcer in your stomach or small
intestine, or if you're pregnant.
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What happens
when the test is performed?
This depends on the
location of the lymph nodes to be biopsied. Fortunately many
lymph nodes, such as those in your neck, armpits, and groin,
are found close to the surface of the skin. These can all be
reached through an incision in the skin.
Some lymph nodes are
located deeper in your body, such as in the middle of your chest.
To reach them, your doctor may insert a tube-like viewing instrument
(a scope) through a slit in the skin into the target area to
see the lymph nodes, and then remove them with tiny surgical
scissors located at the end of the scope. Sometimes removing
lymph nodes for microscopic examination requires surgery.
When lymph nodes beneath
the skin are biopsied, you lie on an examining table. The doctor
cleans the skin at the biopsy site and injects a local anesthetic.
Next, the doctor makes a small incision in the skin and the tissue
just beneath it until he or she can see the lymph node and cut
it out. Following such a biopsy, it's normal to bleed slightly.
After applying pressure to the incision site to stop the bleeding,
the doctor will cover the area with a bandage. You'll usually
be able to go home within several hours.When a biopsy involves
inserting a scope, or surgery, general anesthesia may be required.
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What risks are
there from the test?
The biopsy site will
feel tender for a few days. There's a slight risk of infection
or bleeding. Depending on the location of the lymph node being
removed, there is a slight risk of blood vessel or nerve damage.
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Must
I do anything special after the test is over?
It's normal for the biopsy
site to feel sore afterward, but tell your doctor if it becomes
red or hot, or if you develop a fever. These symptoms could be
signs of infection.
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How
long is it before the result of the test is known?
Results will probably
be ready in several days.
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