Liver Biopsy
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What is the test?
A liver biopsy is a
procedure to obtain a sample of your liver tissue so that it
can be examined under a microscope. Liver biopsy is useful for
determining the cause of hepatitis and for making decisions about
how best to treat it. A liver biopsy can also be used to diagnose
cancer in the liver.
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How do I prepare
for the test?
You will need to sign
a consent form giving your doctor permission to perform this
test. You will most likely have an ultrasound done before the
biopsy so your doctor can see the size of your liver.
Tell your doctor if
you have ever had an allergic reaction to lidocaine or the numbing
medicine used at the dentist's office. If you are taking insulin,
discuss this with your doctor before the test. If you take aspirin,
nonsteroidal anti-inflammatory drugs, or other medicines that
affect blood clotting, talk with your doctor. It may be necessary
to stop or adjust the dose of these medicines before your test.
You will also have blood tests to find out if you are at extra
risk for bleeding after the procedure.
You will be told not
to eat or drink anything after midnight the night before the
test. This is a safety precaution in case you are one of the
rare patients who has a complication that might require surgery
on the same day as the procedure.
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What happens
when the test is performed?
Usually the liver biopsy
is done in a special procedure clinic called the endoscopy area
of a hospital. You wear a hospital gown. You have your blood
pressure and oxygen level monitored with a blood pressure cuff
and a finger clip. An IV (intravenous) line is put into your
arm or hand in case you need to receive some fluid during the
procedure. (You would be likely to need this only if you had
a bleeding problem from the test.)
The liver is located
just under your ribs on the right side. Your doctor taps on your
right rib cage and abdomen to find the edges of your liver. If
your liver is on the small side, the doctor might use an ultrasound
sensor to see exactly where the top and bottom of the liver are.
Medicine through a small
needle is used to numb the skin in one place over your lower
ribs. The numbing medicine usually stings for a second. After
this, the liver biopsy needle is inserted. The biopsy needle
is 5-6 inches long, but it is not put that far inside you. A
small piece of liver tissue is captured inside the needle. The
needle is pulled out and the sample carefully removed.
Most patients feel some
definite soreness or cramping in their side and right shoulder
after this test, but the soreness usually lasts for only 10-15
minutes.
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What risks are
there from the test?
This test is safe for
most patients, but there are some serious complications that
can occur. One in 200 patients has some bleeding from the place
where the needle went into the liver. When this occurs, the blood
usually stays inside the sac that surrounds the liver and causes
this lining to stretch to the point that you feel some pain for
a few days. More serious bleeding occurs in only 1 out of every
1,000-2,500 patients. If you are one of the patients who has
more serious bleeding, there is a chance that you will need surgery
to stop the bleeding. Other risks include injury to the lung,
intestine, or gallbladder. These rarely occur.
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Must
I do anything special after the test is over?
After the biopsy, you
will need to lie on your right side for a full two hours. This
is done so that your weight puts pressure on the liver, reducing
the chances of bleeding. You will be watched for four hours after
that, with your blood pressure getting checked every now and
then to make sure there is no sign that you are bleeding inside.
Usually the doctor will allow you to eat and drink during this
time.
You should not do any
heavy lifting or aerobic exercise for a couple of days, while
your liver is healing.
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How
long is it before the result of the test is known?
Examination of your
liver sample by pathology doctors takes close to five days.
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