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December 2001


Nothing Light About 'Light' Cigarettes
A report recently issued by the National Cancer Institute proves what many people have suspected all along: "light" cigarettes are more a marketing ploy, than an attempt to make smoking safer.

Light and ultralight cigarettes produce lower amounts of tar and nicotine than regular cigarettes when smoked by testing machines. However, this is not the case when a person uses them. This is due to the smoker's desire to get as much of the harmful chemicals as possible, and from the design of the cigarette. Because smokers are addicted to nicotine, not the act of smoking, they usually inhale harder on light cigarettes or simply smoke more of them to get their fix. And the way the cigarettes are designed- with ventilation holes placed where smokers' fingers or lips easily block them - means smokers are often inhaling harder than necessary, regardless of whether or not they are craving more nicotine.

In the 1960s and '70s, studies on light cigarettes showed promising results. Smokers using the reduced strength cigarettes had lower risk of lung cancer risk than those using the full-strength tobacco products. The increasing use of light products was expected to further decrease smoking-related diseases. Unfortunately, this has not come to pass. Lung cancer rates rose until the early 90s. And it was a decrease in smoking in general—not tobacco light—that has caused the decline seen since then.
December 2001 Update

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Shapely Sperm and Fertility
The shape of a man's sperm is the best gauge of fertility, according to a recent study in The New England Journal of Medicine.

Researchers from the National Cooperative Reproductive Medicine Network have found the best sperm structure is an oval head and long straight tail. Unusually shaped sperm — those with very large or small heads, or tails with twists and coils — were not able to fertilize the egg. The World Health Organization (WHO) publishes standards of normal semen measurements, but the guidelines on the quantity of quality semen indicative of fertility have varied throughout the years and have not proved themselves in thorough testing.

The men in the study were more likely to be infertile if fewer than 9 percent of their sperm were well shaped, while they were most likely to be fertile if more than 12 percent of their sperm looked normal.

While there is no surefire way to diagnose fertility, these findings on well-shaped sperm could help standardize the WHO's criteria.
December 2001 Update

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High-Normal Blood Pressure Bad for the Heart
People with high-normal blood pressure are more likely to suffer a heart attack, stroke, or heart failure than those with lower blood pressure, according to recent findings from the Framingham Heart Study.

The researchers followed the cardiovascular events of 6,859 participants of the famed study, which has been monitoring subjects from the Boston suburb for more than 50 years. A third of participants had normal blood pressure (120–129 over 80-84 mm HG), a quarter had high-normal (130–139 over 85–89 mm Hg), and the remainder had optimal blood pressure (less than 120 over less than 80 mm HG). People with high blood pressure were excluded from the study.

Of those in the optimal category, 81 had cardiac events, over a ten-year time period, compared to 136 people in the normal blood pressure category and 180 in high-normal category. In all, people with high-normal blood pressure were two to three times more likely to suffer a heart attack, stroke, or heart failure than those with lower blood pressure. This held true in both men and women, and was consistent in both age groups (35 to 64 and 65 and over), even after researchers adjusted for other cardiovascular risk factors such as smoking and obesity. Indeed, the study found risk increases in a stepwise fashion as blood pressure increases.

Blood pressure reflects how hard your heart is working and what conditions your arteries are in. Risk factors include heavy drinking, smoking, eating a diet high in salt, obesity, and family history. Doctors generally get alarmed only if systolic blood pressure is above 140 mm Hg or if diastolic blood pressure is above 90 mm Hg. However, this study calls for further research to be done to see if patients in the high-normal group benefit from lowering their blood pressure.
December 2001 Update

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Salt Restriction More Potent Than Exercise
Physicians often give patients with hypertension a daunting list of lifestyle changes to help lower their blood pressure: lose weight, exercise more, eat less salt, drink less alcohol, eat more foods rich in calcium, potassium, and magnesium. Of course, these changes do work — people who follow them can reduce their need for medications or even do without blood pressure-lowering drugs. But which of these lifestyle changes gives you the biggest bang for your buck?

University of Colorado researchers recently compared the impact of exercise or moderate salt restriction in 35 healthy older women with high-normal blood pressure or mild hypertension (systolic blood pressure 130–159 mm Hg), none of whom were using drugs to lower their blood pressure. Half the women exercised for three months — starting at 30 minutes a day three or four times a week and working up to 45 minutes a day every day, if possible. The other half tried to reduce their daily salt intake to less than 2.4 grams of sodium (the amount in a level teaspoon of table salt) without otherwise changing their diets. All were asked to try to avoid gaining or losing weight.

The clear winner, reported in the American Journal of Cardiology, was sodium restriction. Among the women who ate less salt, average systolic blood pressures fell 16 mm Hg, compared with a still-respectable 5 mm Hg in the exercise group. By the study's end of the study, systolic blood pressure was lower in 88% of the women who ate less salt and in 55% of the exercisers.

So if you're trying to lower your blood pressure, should you just forget about exercise and work harder at eating less salt? No. Exercise has other benefits besides lowering blood pressure — it can help control weight, improve the cholesterol profile, stave off diabetes, and keep bones strong. The real message from this study is that everyone should exercise, but that people who are trying to control blood pressure should lower their sodium intake, too.

December 2001 Update

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Aggressive Therapy for Older Hearts
There's no question coronary artery bypass grafting and angioplasty can relieve the pain of angina, prevent heart attacks, and add years to the lives of people with blocked coronary arteries. But most studies have excluded people over age 70, so the benefits of aggressive therapy is less clear in the older patient.

Two studies from Switzerland and Canada provide good news for older people who may need bypass surgery or angioplasty. Swiss researchers compared the effects of medical therapy and invasive therapy among more than 300 men and women with angina, all of whom were age 75 or over. They reported the results in the journal Lancet. After six months, the frequency and severity of chest pain had lessened and the quality of life had improved in both groups. But the improvements were substantially greater, and the heart attack rate substantially lower, among those who had undergone bypass surgery or angioplasty.

The Canadian study, which appeared in the Canadian Medical Association Journal, compared the effects of bypass surgery on patients in their 80s and those in their 70s. The investigators found it as safe and effective for octogenarians as it was for septuagenarians and reported that it cost about the same in either group.

Neither of these studies provides blanket assurance that an invasive procedure like bypass surgery or angioplasty is right for every older person with blocked coronary arteries. Older candidates for bypass surgery or angioplasty may want to focus on quality-of-life issues. Recovery, for example, may be a completely different experience for older people.
December 2001 Update

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