Granulomatosis with polyangiitis (Wegener's) is a relatively rare disease marked by inflammation of the blood vessels. The condition is potentially life-threatening.
In Granulomatosis with polyangiitis (Wegener's), inflammation damages the walls of small- and medium-sized arteries and veins. This damage interferes with normal blood supply to nearby tissues. As a result, tissues in many parts of the body may be injured and destroyed.
Tissues affected by Granulomatosis with polyangiitis (Wegener's) contain islands of inflamed cells. These are called granulomas.
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