Dupuytren's contracture is one of the most common chronic hand conditions that affects tissues in the palm of the hand. Stages include thickening and pitting of the skin, then a painless nodule, followed by firm cords that develop along the tendons responsible for bending the fingers toward the palms. Over time, the cords tighten, bending the fingers inward. A new medication (an enzyme produced by Clostridium histolyticum), a bacterial cause of deadly gas gangrene offers an alternative treatment.
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