Harvard Health Letter

Bad mix: Blood thinners and NSAIDs

Use of blood thinners requires caution with other drugs, especially painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs). Taking blood thinners and NSAIDs together can raise the risk of bleeding. Acetaminophen (Tylenol) can be used as an alternative, but it comes with the risk of increasing the effect of blood thinners. When painkillers are needed, it’s best to use the lowest dose that reduces symptoms, and to stop taking them if the symptoms subside. Doctors should supervise the use of the two drugs.
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