Cholecystitis is an inflammation of the gallbladder. The gallbladder is the small sac-like organ located in the upper right side of the abdomen, just below the liver. It is attached to the main duct that carries bile from the liver into the intestine. The gallbladder temporarily stores bile, which is a liquid that contains a fat-digesting substance produced in the liver. During a meal, the gallbladder contracts, and bile moves from the gallbladder through small, tube-like passages (called the cystic duct and the common bile duct) into the small intestine. Here, bile mixes with food to help break down fats.
Cholecystitis usually develops when a person has gallstones, which are rock-like deposits that form inside the gallbladder. If a gallstone blocks the cystic duct (the outflow from the gallbladder), bile becomes trapped in the gallbladder. Chemicals in the trapped bile or a bacterial infection can then lead to inflammation of the gallbladder.
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