Memory

Stephanie Watson

Late-life depression may signal memory loss or dementia ahead

Depression can strike at any age. Children can develop it, as can octogenarians. No matter when it starts, depression can drain the joy and pleasure from life. The first appearance of depression later in life may also be a signal of memory loss or dementia down the road. According to a study in the Archives of General Psychiatry, dementia is more common among people who become depressed in middle age or later in life than among those who aren’t depressed. Depression is often overlooked in older adults, so it’s important to be on the lookout for warning signs, like feelings of hopelessness, loss of interest in activities, trouble sleeping, and more. It’s important to treat depression in individuals with the beginning of dementia, and older individuals who are depressed should be evaluated for dementia.

Robert Shmerling, M.D.

Brain disease deaths high in pro football players

How’s this for a mind-bender: Lou Gehrig may not have had Lou Gehrig’s disease. Instead, the disease that ended his life may have been chronic traumatic encephalopathy (CTE). This brain disease is caused by repeated concussions—Gehrig sustained at least four during his baseball career—or other head injuries. It can cause symptoms very similar to those of amyotrophic lateral sclerosis (ALS), now commonly called Lou Gehrig’s disease. More evidence of a connection between CTE and ALS comes from a new study of almost 3,500 retired professional football players, all of whom had played for at least five years in the National Football League. Among the 334 who died during the course of the study, the risk of death from Alzheimer’s disease or ALS was nearly four times higher than expected. Players who manned a “speed” position (such as quarterbacks or receivers) had a risk of dying from Alzheimer’s disease or ALS that was more than three times higher than those playing “non-speed” positions (such as linemen).

Stephanie Watson

A sluggish, unsteady walk might signal memory problems

Is there a spring in your step—or a wobble in your walk? The speed and stability of your stride could offer important clues about the state of your brain’s health. According to new research, an unsteady gait is one early warning sign that you might be headed for memory problems down the road. A group of studies reported last week at the Alzheimer’s Association International Conference in Vancouver, Canada, revealed a strong link between walking ability and mental function. What’s behind this connection? Walking is a complex task that requires more than just moving the leg muscles. Walking requires scanning the environment for obstacles and safely navigating around them, all while talking and carrying out various other tasks. The studies found that walking rhythm was related to information processing speed; walking variations and speed were associated with executive function (the mental processes we use to plan and organize); and walking speed became significantly slower as mental decline grew more severe.

Christine Junge

Can computer games keep your brain fit?

Computer games are being touted as a way to keep the body fit. Can they do the same for your brain? Most experts say “Not so fast.” As described in Improving Memory: Understanding age-related memory loss, a new Special Health Report from Harvard Medical School, people who play these games might get better at the tasks they practice while playing, but the games don’t seem to improve users’ overall brain skills, such as attention, memory, use of language, and ability to navigate. To stretch and exercise your brain, choose an activity you enjoy—reading, playing cards, or doing crossword puzzles are some good examples. If you’re feeling ambitious, try learning to speak a new language or play a musical instrument. Most of these activities come at a much lower cost than brain-training programs, and you’ll probably find them to be a lot more enjoyable, too.

Patrick J. Skerrett

National plan aims to bolster fight against Alzheimer’s

By the year 2050, experts estimate that 16 million Americans will be living with this Alzheimer’s disease. In an effort to head off the explosion, President Obama has signed into law the National Alzheimer’s Project Act. This ambitious project aims to attack Alzheimer’s disease by improving early diagnosis, finding effective prevention and treatment strategies, providing better support for family caregivers, and more. A newly released draft of the project, which a panel of experts is reviewing this week, sets a 2025 deadline for achieving these and other goals. One big drawback—the act doesn’t provide concrete details about how to fund the research and implementation efforts needed to meet the goals.

Annmarie Dadoly

Is it Alzheimer’s, or just a memory slip?

Everyone has moments of forgetfulness—misplaced keys, a forgotten errand, the name of that movie you want to recommend but can’t get off the tip of your tongue. A certain amount of forgetfulness seems to be a normal byproduct of aging. But how do you know is forgetfulness signals something more serious, like Alzheimer’s disease or another form of dementia? According to “A Guide to Alzheimer’s Disease,” an updated Special Health Report from Harvard Medical School, by exploring several questions you may be able to get a clearer sense of normal versus worrisome forgetfulness: Is my loved one worried about the memory loss? Is he or she getting lost in familiar territory? Are word-finding problems common? Is your loved one losing the ability to socialize, or interest in it?

Patrick J. Skerrett

At Harvard Forum, experts debate how much vitamin D is enough

A panel discussion at Harvard School of Public Health called “Boosting Vitamin D: Not Enough or Too Much?” highlights the current controversy over the once-overlooked sunshine vitamin. A panel of experts assembled by the Institute of Medicine recommends a daily dose of 600 IU per day for everyone from ages 1 to 70 and 800 IU for those over 70. Other experts think the IOM recommendation is too low. One way to get vitamin D is to spend a few minutes a day outside in the sun, but that’s a hot-button issue because sun exposure is a cause of skin cancer.

Ann MacDonald
Patrick J. Skerrett

Cell phone use stimulates brain activity

An elegant new study showing that a cell phone can stimulate brain activity is certain to heat up the debate about whether or not cell phone use is linked to cancer. It’s an important signal that it’s high time scientists take a harder look at how the energy radiated by a cell phone, a mobile phone, or any other energy-emitting device we hold next to our heads affects the brain.

Peter Wehrwein

Football and concussions: Old school, new school, and a conversation with Jerry Kramer

Tomorrow night at 6:30 p.m., tens of millions of television sets will be turned on as Americans sit down and participate in that unofficial national holiday called “watching the Super Bowl.” For many, it’s an excuse to see funny ads and the half-time show and to eat (how many of those spanking new Dietary Guidelines will be broken?), drink, and socialize. But […]