Alzheimer’s Disease

Patrick J. Skerrett

National plan aims to bolster fight against Alzheimer’s

By the year 2050, experts estimate that 16 million Americans will be living with this Alzheimer’s disease. In an effort to head off the explosion, President Obama has signed into law the National Alzheimer’s Project Act. This ambitious project aims to attack Alzheimer’s disease by improving early diagnosis, finding effective prevention and treatment strategies, providing better support for family caregivers, and more. A newly released draft of the project, which a panel of experts is reviewing this week, sets a 2025 deadline for achieving these and other goals. One big drawback—the act doesn’t provide concrete details about how to fund the research and implementation efforts needed to meet the goals.

Annmarie Dadoly

Is it Alzheimer’s, or just a memory slip?

Everyone has moments of forgetfulness—misplaced keys, a forgotten errand, the name of that movie you want to recommend but can’t get off the tip of your tongue. A certain amount of forgetfulness seems to be a normal byproduct of aging. But how do you know is forgetfulness signals something more serious, like Alzheimer’s disease or another form of dementia? According to “A Guide to Alzheimer’s Disease,” an updated Special Health Report from Harvard Medical School, by exploring several questions you may be able to get a clearer sense of normal versus worrisome forgetfulness: Is my loved one worried about the memory loss? Is he or she getting lost in familiar territory? Are word-finding problems common? Is your loved one losing the ability to socialize, or interest in it?

Carolyn Schatz

The dangers of hospital delirium in older people

Many older people develop delirium when they are hospitalized. Delirium is a sudden change in mental status characterized by confusion, disorientation, altered states of consciousness (from hyperalert to unrousable), an inability to focus, and sometimes hallucinations. Hospital delirium is especially common among older people who’ve had surgeries such as hip replacement or heart surgery, or those who are in intensive care. Inflammation, infection, and medications can trigger hospital delirium as can potentially disorienting changes common to hospital stays, including sleep interruptions, unfamiliar surroundings, disruption of usual routines, separation from family and pets, and being without eyeglasses or dentures. Although delirium often recedes, it may have long-lasting aftereffects, including premature death and poorer outcomes, such as dementia and institutionalization.

Peter Wehrwein

Alzheimer’s disease in its later stages: Some advice for caregivers

Alzheimer’s disease is a “disease of behaviors” that can wear down family and loved ones. In a talk called “Dementia and Cognitive Decline (Aging Gracefully)” Barbara Moscowitz, coordinator of geriatric social work for the Geriatric Medicine Unit at Harvard-affiliated Massachusetts General Hospital, offered helpful insights and tips into caring for people with Alzheimer’s disease. Moscowitz drew not only her 30 years of professional experience, but also on the personal experience of helping take care of her mother, who suffered from dementia the last several years of her life.

Peter Wehrwein

Football and concussions: Old school, new school, and a conversation with Jerry Kramer

Tomorrow night at 6:30 p.m., tens of millions of television sets will be turned on as Americans sit down and participate in that unofficial national holiday called “watching the Super Bowl.” For many, it’s an excuse to see funny ads and the half-time show and to eat (how many of those spanking new Dietary Guidelines will be broken?), drink, and socialize. But […]

Michael Craig Miller, M.D.
Ann MacDonald

Alzheimer’s study on biomarkers generates debate

A study about a three-protein signature that might help identify people with Alzheimer’s,  published in the August issue of the Archives of Neurology, has generated quite a bit of discussion in the blogosphere.  I thought readers might want to follow the discussion, so I’ve shared some links to representative posts. (We will be covering the […]