On Monday, Dr. Joseph E. Murray passed away at age 93. A long-time member of the Harvard Medical School faculty, Murray pioneered the field of organ transplantation. This great achievement, for which he was honored with the Nobel Prize in Medicine in 1990, has given the gift of life to hundreds of thousands of people destined to die young. But his success did not come easily. Not only did Murray attempt to do something others judged impossible, but kept trying in the face of sometimes withering criticism from peers. Murray’s team successfully performed the first organ transplant, a kidney donation from one young man to his twin brother. Over the next decade, Murray and his colleagues learned how to quiet the immune system to make it possible to transplant organs between unrelated people.
Anthony Komaroff, M.D.
Posts by Anthony Komaroff, M.D.
Sometimes, the Nobel Prize in Physiology or Medicine is awarded for a discovery or invention that already is improving the practice of medicine and saving lives. Sometimes it is awarded for very basic research that might someday affect medical practice and human health. Such is the case with this year’s Nobel Prize in Physiology or Medicine, which was awarded to Sir John Gurdon of Great Britain and Dr. Shinya Yamanaka. If I had to put into one sentence the message of today’s Prize, it would be this: our cells are a lot smarter and more flexible than we once imagined, and capitalizing on that fact could greatly improve the treatment of many human diseases. The work of Gurdon and Yamanaka led the way to today’s work on stem cells, which could someday be used to treat human diseases. The 2012 Nobel Prize in Medicine, like many before it, demonstrates that people with the curiosity and courage to ask what appear to be ridiculous questions, and a society that supports their work, can change our world for the better.
Today’s ruling by the Supreme Court that largely upholds the Patient Protection and Affordable Care Act should be viewed as a landmark event—whether one agrees with it or not. The Supreme Court’s ruling means that many more people will have health insurance; that health care will continue to be provided largely by the private sector; and that insurance companies won’t be able to deny an individual coverage because he or she has a chronic medical condition, drop coverage if an individual becomes sick, or put limits on the amount of lifetime coverage a person can get. It also means that individuals without health insurance will have to pay for it, and that many employers who do not currently offer health insurance as a benefit will be required to do so, or pay a stiff penalty.
These days, when I must give one of my patients the bad news that he or she has type 2 diabetes, the response is sometimes along the lines of “Well, I figured it was just a matter of time before that happened.” Many people suspect they are on a collision course with type 2 diabetes, […]
Although short-term studies suggest that switching from sugar to calorie-free sweeteners can help people lose weight, the December 2011 Harvard Health Letter explores the possibility that it may actually promote weight gain. Use of super-sweet artificial sweeteners may desensitize users to sweetness. Healthful foods like fruits and vegetables may become unappetizing by comparison. As a result, the overall quality of the diet may decline. The calories removed from the diet by the sugar-for-sweetener swap may sneak back in, in the form of refined carbohydrates and low-quality fats. Another concern is that artificial sweeteners could cause weight gain by directly stimulating the development of new fat cells.
In the movie “Wedding Crashers,” Owen Wilson and Vince Vaughn made party crashing seem like harmless fun. A different sort of party crasher—microbes with names like Campylobacter and Salmonella (pictured to the right)—sicken nearly 50 million Americans each year. Holiday buffets and dinners are a more inviting setting for the microbes that cause food poisoning […]
Family and togetherness are key themes for the holidays. That can make the holidays awfully difficult for people who are grieving the loss of a loved one. My father passed away a month before the holidays. We still shared presents, ate large meals, visited with friends, even sang carols—but it was all pretty subdued. “If […]
The new science of social networks is demonstrating how personal interconnections can affect our health. Ideas and habits that influence health for better or for worse can spread through social networks in much the same way that germs spread through communities. An article in the December issue of the Harvard Men’s Health Watch explores how social networks can affect weight and mood. A study of people taking part in the Framingham Heart Study found that among participants who had a friend become obese, their chance of becoming obese rose by 57%. A different study from Framingham showed that happiness can also spread across social networks. Research into social networks could help experts some day use them to improve public health.
With Veterans Day and Halloween behind us, we are moving full steam ahead to the holidays, the stretch from Thanksgiving to New Year’s Day (or Super Bowl Sunday, depending on your perspective). The holidays can be a wonderful time, full of friends, family, and fun. But they can also generate pressures and situations that undermine health. To help you enjoy a healthy and happy holiday season, Harvard Health Publications is offering three Special Health Reports that focus on common holiday challenges: depression, overuse of alcohol, and healthy eating.
For years, Dr. Anthony Komaroff has answered his patients’ questions one-on-one. With the launch of Ask Doctor K, a daily newspaper column that appears in 450 newspapers, he will be answering questions from people across the U.S and beyond via daily newspaper and the Internet (at AskDoctorK.com). Dr. Komaroff is a practicing physician, Professor of Medicine at Harvard Medical School, and Editor in Chief of Harvard Health Publications. In the column, he will offer clear answers and straight advice to readers’ questions, talk about new treatments that are available today or will be soon, and focus on proven changes in lifestyle that can keep readers healthy, help them cope with chronic diseases, and improve their quality of life.