Harvard Men's Health Watch

In the journals: High-dose vitamin E may slow Alzheimer's decline

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Adding vitamin E to standard Alzheimer's drugs modestly slows the decline in daily functioning caused by dementia, according to a study in The Journal of the American Medical Association.

The study involved over 600 adults, almost all of them men. Their average age was 79, and all had been diagnosed with mild or moderate Alzheimer's disease. They were already taking one of the standard Alzheimer's medications, such as donepezil (Aricept).

The men were assigned at random to get one of four treatments in addition to their Alzheimer's drug: 2,000 international units (IU) a day of vitamin E, an Alzheimer's drug called memantine (Namenda), both vitamin E and memantine, or an inactive placebo pill.

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