Amyloidosis

Amyloidosis is a disease in which an abnormal protein called amyloid accumulates in body tissues and organs. The protein deposits can be in a single organ or dispersed throughout the body. The disease causes serious problems in the affected areas. As a result, people with amyloidosis in different body parts may experience different physical problems: Brain - Dementia Heart - Heart failure, an irregular or unstable heart rhythm, enlarged heart Kidneys - Kidney failure, protein in the urine Nervous system - Numbness, tingling or weakness from nerve disease Digestive system - Intestinal bleeding, intestinal obstruction, poor nutrient absorption Blood - Low blood counts, easy bruising or bleeding Pancreas - Diabetes Musculoskeletal system - Joint pain or swelling, weakness Skin - Lumps or purple discoloration No one knows what causes amyloidosis. To make matters more complex, amyloidosis is not a single disease, and there are many different types of amyloid protein's that can be involved. For example, Alzheimer's disease and Creutzfeldt-Jakob disease (a rare cause of dementia linked to viruses living in livestock) are two distinct conditions characterized by amyloid deposits in the brain, but the proteins involved are different.
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